A sleek modern design envelopes the packaging of this hemorrhoid cream, giving the feeling that you are in on a hot new secret. Claiming to calm inflamed hemorrhoid tissues immediately upon contact to accelerate healing, it is made up of natural aesthetics to make bowl movements more comfortable. Immediate relief is a promise you can’t scoff at. Could it be too good to be true? Scouring the web for proof that this product does as it claims, we stumbled upon some real-life reviews. While many agreed that the results were real, even if the time frame was not always accurate, others said it had no effect or actually made symptoms worse. Still, with an above average success rate, it is worth a closer look.

ZenMed Ziro Ingredients

Ziro contains:

  • Active Ingredient: Witch Hazel Distillate
  • Purified water
  • Extracts of sage
  • Coltsfoot
  • Yarrow
  • Balm mint
  • Chamomile
  • Rosemary
  • Althea
  • Wild thyme and horsetail
  • Vegetable glycerin
  • Certified organic sunflower oil and aloe vera gel
  • Vitamins A, D3, and E
  • Soy Lecithin
  • Cocoa butter
  • Stearic acid
  • Octyl Palmitate
  • Allantoin
  • Benzyl Alcohol
  • Phenoxyethanol
  • Ethyl Hexyl Glycerin

There is no indication of how much of these ingredients are in each bottle.


This cream can be applied up to six times daily, before or after a bowel movement. The site recommends you clean area gently and wipe dry before you apply the cream. Wash hands before and after application.

Side-effects of the three active ingredients can include:

  • Allergic skin reactions
  • Contact dermatitis
  • Skinirritation
  • Small possibility of increased cold sore symptoms


One bottle of Ziro is set at $34.95 which is considered a one month supply. There is no indication that this cream can be purchased in larger quantities or weight.

ZenMed Ziro Guarantee

A 60 day money-back guarantee is offered for this product.  Although relief is said to be immediate, with results seen between 3-4 days, the site does not give a recommendation as to extended use of this product, however, given the bottle comes in a one month supply, our best guess is that consumers are advised to make use of all contents. If this is the case, the 60-day window is a slim one.


With the above mentioned higher than average success rate also comes a few inconveniences that lessen the appeal of this product. The downside is that it must be applied several times in a day as opposed to oral options where you pop one or two pills and you are done. The largest inconvenience factor lies in its usage as many people do not have the abilities or freedom of schedule to perform continuous applications. Inconveniences aside, the essence of this product treats the effects and not the root cause of the problem

In addition, the price is not any more affordable than less invasive pill options. Overall, the appeal is just not there. Perhaps if you are a homebody and have the time to perform multiple applications, the benefits outweigh the annoyances, but for anyone with an active lifestyle, this product is not the miracle cure it’s made up to be.

Click here to learn about our Top Hemorrhoid Treatment products.