Nupercainal Bio-Active is labeled for the temporary relief of the pain and itching associated with hemorrhoids and a few other anorectal discomforts.

The cream and anal suppositories are indicated (by the manufacturer) to target the pain and discomfort caused by anal irritation.

Considered homeopathic medicine, Nupercainal Bio-Active uses a proprietary blend of natural ingredients to reduce anal discomfort.

Nupercainal Bio-Active Formula

Nupercainal Bio-Active contains the following ingredients

  • Hamamelis virginiana
  • Proprietary herbal blend
  • Echinacea purpurea
  • Centella asiatica
  • Sambucus nigra

However, according to WebMD, none of the ingredients provided are proven to be effective for the relief of hemorrhoids or any anorectal disorders.


After cleansing the area and rinsing, apply the cream up to six times a day. As for the suppository, there was no dosage information found during our research.


Nupercainal Bio-Active costs $10.60, plus $5.99 for shipping. This is considerably lower than most other similar products. It is too low in fact, to allow for the business to profit and continue being able to afford production.

Nupercainal Bio-Active Guarantee

There is no guarantee offered for Nupercainal Bio-Active, cream or suppository.


Nupercainal Bio-Active does not contain any beneficial ingredients, and it is priced way to low in comparison to similar products.

Click here to learn about our Top Hemorrhoid Treatment products.